Donor factor V leiden mutation and vascular thrombosis following liver transplantation
نویسندگان
چکیده
منابع مشابه
Factor V Leiden, MTHFR C677T and Prothrombin Gene Mutation G20210A in Iranian Patients with Venous Thrombosis
Background: Factor V Leiden, Prothrombin gene (G20210A) and MTHFR (C677T) polymorphism are the main biomarkers for evaluation of tendency for venous thromboembolism. We aimed to investigate the frequency of mutations in factor V Leiden, Prothrombin G20210A and MTHFR C677T and identify the genetic status for these mutations in patients with venous thrombosis. Methods: This study was carried out...
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A polymorphism in coagulation factor V, factor V Leiden (FVL), is the major known genetic risk factor for thrombosis in humans. Approximately 10% of mutation carriers experience clinically significant thrombosis in their lifetime. In a small subset of patients, thrombosis is associated with coinheritance of other prothrombotic gene mutations. However, the potential contribution of additional ge...
متن کاملSpontaneous thrombosis in mice carrying the factor V Leiden mutation.
A polymorphism in coagulation factor V, factor V Leiden (FVL), is the major known genetic risk factor for thrombosis in humans. Approximately 10% of mutation carriers experience clinically significant thrombosis in their lifetime. In a small subset of patients, thrombosis is associated with coinheritance of other prothrombotic gene mutations. However, the potential contribution of additional ge...
متن کاملPortal vein thrombosis complicating islet transplantation in a recipient with the Factor V Leiden mutation.
A 31-year-old Native American/ white female with Type 1 diabetes mellitus of 26 years duration enrolled in the international multicenter trial of the Immune Tolerance Network (NS01) to replicate the Edmonton Protocol for islet transplantation. She used oral contraceptives. She had undergone two prior islet transplant procedures complicated by sirolimus induced mucositis, diarrhea, and anemia, t...
متن کاملFactor V Leiden mutation in pregnancy.
Normal maternal adaptation to pregnancy significantly increases the risk for thrombus formation. Inherited thrombophilias further increase risk for deep venous thrombosis and adverse outcome in pregnancy. Factor V Leiden mutation is the most common inherited thrombophilia, occurring in approximately 5% of the White and 1% of the Black populations. Nurses should be knowledgeable about screening ...
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ژورنال
عنوان ژورنال: Liver Transplantation and Surgery
سال: 1998
ISSN: 1074-3022
DOI: 10.1002/lt.500040108